Creatine is a powder that is used by many athletes today to improve their sports training. It has been proven time and time again to increase strength, increase power endurance and help athletes gain weight.
I started using creatine in 1993 after my senior year playing football at San Diego State University. It was the new hot thing in the then top muscle magazine Muscle Media 2000. Honestly it worked and I have used it on and off for years.
I saw an increase in my bench press which took my repetitions at 315 lbs. for 7 reps to 11 reps in a short period of time. Not bad for something completely natural and legal!
There are many different versions of creatine out there but two of the most popular are creatine ethyl ester and creatine monohydrate. Both have their places and certain athletes like one version over another.
In a nutshell some athletes feel that creatine monohydrate makes them stronger where creatine ethyl ester makes them feel stronger without feeling bloated.
I’ve have many of my athlete over the years use creatine and most like it. One kid in particular that plays linebacker for the Rice University Owls likes that monohydrate version better. However another kid I train that plays for University of Nevada likes the creatine ethyl ester.
Everyone will have their own opinion about creatine. Here is some good information to learn more about these versions of creatine before starting out adding it to your sports diet.
Creatine Ethyl Ester is made up of three amino acids – Arginine, Glycine and Methionine. Our liver has the ability to combine these three amino acids and make creatine. The other way we get creatine is from our diet.
What is it and where does it come from?
Creatine Ethyl Ester HCL (CEE) is creatine monohydrate with an ester attached. Esters are organic compounds that are formed by esterification – the reaction of carboxylic acid and alcohols.
However, regular creatine monohydrate is absorbed poorly by the body – and its effectiveness is dependant upon the cells ability to absorb it. The poor absorption rate of regular creatine monohydrate requires the creatine user to ingest large dosages of creatine to achieve desired effect.
Because creatine draws water to the cell, and because most ingested creatine monohydrate is not absorbed, unabsorbed creatine will sit outside of the target cell with the water, and this will result in the “creatine bloat.”
What does it do?
Long-term clinical studies have proven that creatine monohydrate is safe for use by persons free of medical complication, but why would you want to ingest more creatine monohydrate than you have to simply because your creatine is inefficient?
Creatine ethyl ester is creatine monohydrate with an ester attached. The attachment of an ester is significant, because esters are found in the fat tissue of animals. But, why is this important? What role does this have in the absorption of creatine?
All substances that you put into your body will affect its operation. There are three ways that substances can affect a cells operation. They are:
- Ligand binding to protein receptor sites.
- Secondary messenger / metabotropic systems
- Passive permeation of the cell wall via lipids
When a substance enters the body and affects the bodies operation, it is known as a ligand. The soma and dendrites of the cell have protein receptor sites to which ligands can bind. The process of a ligand binding with a receptor site is akin to a lock and key: only keys of a certain shape work with certain locks. When they work and cause the cells stimulation they are called agonists. When they block the cell from functioning they are called antagonists.
When a ligand binds with the receptor site of a target cell, the cell, in the simplest of cases, changes its shape, opens up its ion channels and changes its function. In so-called “secondary messenger” or metabotropic cells, the ligand binds with the receptor site and an internal protein known as a g-protein is released. This released protein then binds to an internal site inside of the cell, and then the cell changes its behavior by opening its ion channels. Cells that operate in this way are known as metabotropic cells because their operation requires metabolic energy.
Passive permeation is a process that describes the diffusion of a substance across a cell membrane through the use of lipids as transport mechanisms. Because no “work” is being done by the cell in this model, this model is called passive permeation.
Why CEE instead of Monohydrate?
Works faster and is more efficiently absorbed.
This is likely because the esterification of creatine, CEE, will increase its lipopholic abilities, and thus esterified creatine will use fat more efficiently to permeate the cell wall and exert its effects on cellular function than its unesterified creatine monohydrate counterpart.
Requires a smaller dosage
This is likely because regular creatine monohydrate is absorbed poorly by the body, and its effectiveness is dependent on the cells’ ability to absorb it. As a result, the poor absorption rate of regular creatine monohydrate requires users to ingest larger amounts of creatine monohydrate (5 to 20 grams, daily) to achieve a desired effect, versus the three to six grams of esterfied creatine, daily.
Eliminates the infamous “water bloat” look
Thus is likely because creatine draws water into the cell (cell volumization), and because most ingested creatine monohydrate is not all absorbed, any unabsorbed creatine will sit outside of the target cell with the water. As a result, this may cause the dreaded “creatine water bloat.” Whereas, esterfied creatine is said to pull nearly all of the water into the muscle cell, thereby creating a harder, more solid appearance of muscularity.
In the end my advice to you would be taking one version for 4-6 weeks and monitor your training. Then take 2 weeks off and start the same cycle of the other version and see what works best for you!
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